Zero human or added animal materials.
Zero transfer step. Zero excuses.
It's not just about factor VIII therapy. It's an attitude.

Watch XYNTHA® Solofuse™ in action

XYNTHA is manufactured using Chinese hamster ovary (CHO) cells from a master cell bank. These cells are grown in an albumin-free culture. XYNTHA contains trace amounts of hamster protein. You may develop an allergic reaction to these proteins. Tell your doctor if you have had an allergic reaction to hamster protein.

It's the factor VIII with state-of-the-art purification. It comes with all-in-one reconstitution. It's XYNTHA. Are You In?

Xyntha^® Antihemophilic Factor (Recombinant), Plasma/Albumin-Free and diluent come together. Vials are eliminated. Imagine life without the transfer step. XYNTHA Solofuse™—it's the next step in reconstitution convenience. Now available with 250-IU and 500-IU dosing options. Also available in 1000 IU, 2000 IU, and 3000 IU.

See how it's done

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XYNTHA Solofuse comes in a travel-ready kit with everything you need to infuse on the go.

Get a FREE demo kit

XYNTHA has been demonstrated in clinical trials to work successfully and control bleeds with 1 or 2 infusions in patients with hemophilia A.

Learn how XYNTHA can work for you

The reconstitution convenience of XYNTHA Solofuse comes with next-generation purification. XYNTHA is completely albumin-free from start to finish. It also goes through 2 state-of-the-art steps designed with viral safety in mind.

See how XYNTHA is made

Savings on factor^†
FREE demo kit
Unofficial survival guide

^†Terms and conditions can be found at XYNTHA.com.

What is XYNTHA?

Xyntha^® Antihemophilic Factor (Recombinant), Plasma/Albumin-Free is indicated for the control and prevention of bleeding episodes in patients with hemophilia A (congenital factor VIII deficiency or classic hemophilia) and for surgical prophylaxis in patients with hemophilia A.

XYNTHA does not contain von Willebrand factor and, therefore, is not indicated in von Willebrand's disease.

Important Safety Information for XYNTHA

Allergic reactions are possible with XYNTHA. Signs of an allergic reaction may include hives, rash with itching, chest tightness, difficulty breathing, faintness, or fast heartbeat. XYNTHA contains trace amounts of hamster protein. You may develop an allergic reaction to these proteins. Tell your doctor if you have had an allergic reaction to hamster protein.
Call your doctor right away if bleeding is not controlled after using your factor VIII replacement therapy; this may be a sign of an inhibitor. Inhibitors have been observed in patients receiving factor VIII products, including XYNTHA.
The most common adverse reaction in study 1 (safety and efficacy study) is headache (24% of subjects) and in study 2 (surgery study) is fever (41% of subjects). Other common side effects of XYNTHA include nausea, vomiting, diarrhea, or weakness.
XYNTHA is an injectable medicine administered by intravenous (IV) infusion. Local irritation may occur when infusing XYNTHA after reconstitution in XYNTHA Solofuse.

Please see full Prescribing Information for XYNTHA and XYNTHA Solofuse.

Need help accessing Pfizer medicines?
Pfizer's RSVP program may be able to help.
Call 1-888-327-RSVP (7787) or visit www.HemophiliaVillage.com/RSVP

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

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Marketed by Pfizer Inc.
September 2011

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions about patient care must be made with a health care provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

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